AboutWorkNewsContactCareer

Publications

  • Acute Kidney Injury Leading to CKD is Associated with a Persistence of Metabolic Dysfunction and Hypertriglyceridemia
    A Harzandi, G Bidkhori, S Lee, S Saha, B Hendry, A Mardinoglu, S Shoaie, ...Available at SSRN 3708521
  • Applications of Genome-Wide Screening and Systems Biology Approaches in Drug Repositioning
    E Mohammadi, R Benfeitas, H Turkez, J Boren, J Nielsen, M Uhlen, ... Cancers 12 (9), 2694
  • Systems Biology Approaches to Understand the Host–Microbiome Interactions in Neurodegenerative Diseases
    D Rosario, J Boren, M Uhlen, G Proctor, D Aarsland, A Mardinoglu, ... Frontiers in Neuroscience 14, 716
  • A systems biology approach for studying neurodegenerative diseases
    S Lam, A Bayraktar, C Zhang, H Turkez, J Nielsen, J Boren, S Shoaie, ... Drug Discovery Today
  • In vitro neuroprotective effects of farnesene sesquiterpene on alzheimer’s disease model of differentiated neuroblastoma cell line
    ME Arslan, H Türkez, A Mardinoğlu International Journal of Neuroscience, 1-10
  • Neuroprotective effects of boron nitride nanoparticles in the experimental Parkinson’s disease model against MPP+ induced apoptosis
    R Küçükdoğru, H Türkez, ME Arslan, ÖÖ Tozlu, E Sönmez, A Mardinoğlu, ... Metabolic Brain Disease, 1-11
  • An atlas of human metabolism
    JL Robinson, P Kocabaş, H Wang, PE Cholley, D Cook, A Nilsson, ... Science Signaling 13 (624)
  • Nonpharmacological treatment options for Alzheimer's disease: from animal testing to clinical studies
    H TÜRKEZ, ME Arslan, A Di Stefano, I Cacciatore, A MARDİNOĞLU Turkish Journal of Zoology 44 (2), 81-89
  • Classification of clear cell renal cell carcinoma based on PKM alternative splicing
    X Li, B Turanli, K Juszczak, W Kim, M Arif, Y Sato, S Ogawa, H Turkez, ... Heliyon 6 (2), e03440
  • Novel anti-Alzheimer phenol-lipoyl hybrids: Synthesis, physico-chemical characterization, and biological evaluation
    A Pagoni, L Marinelli, A Di Stefano, M Ciulla, H Turkez, A Mardinoglu, ... European Journal of Medicinal Chemistry 186, 111880
  • Systems biology based drug repositioning for development of cancer therapy
    B Turanli, O Altay, J Borén, H Turkez, J Nielsen, M Uhlen, KY Arga, ... Seminars in Cancer Biology
  • Discovery of functional alternatively spliced PKM transcripts in human cancers
    X Li, C Zhang, W Kim, M Arif, C Gao, A Hober, D Kotol, L Strandberg, ... BioRxiv, 613364
  • A network-based cancer drug discovery: from integrated multi-omics approaches to precision medicine
    B Turanli, K Karagoz, G Gulfidan, R Sinha, A Mardinoglu, KY Arga Current pharmaceutical design 24 (32), 3778-3790
  • Systems biology in hepatology: approaches and applications
    A Mardinoglu, J Boren, U Smith, M Uhlen, J Nielsen Nature Reviews Gastroenterology & Hepatology 15, 365–377
  • A pathology atlas of the human cancer transcriptome
    M Uhlen, C Zhang, S Lee, E Sjöstedt, L Fagerberg, G Bidkhori, ... Science 357 (6352)
  • Transcriptomics resources of human tissues and organs
    M Uhlén, BM Hallström, C Lindskog, A Mardinoglu, F Pontén, J Nielsen Molecular systems biology 12 (4), 862
  • The gut microbiota modulates host amino acid and glutathione metabolism in mice
    A Mardinoglu, S Shoaie, M Bergentall, P Ghaffari, C Zhang, E Larsson, ... Molecular systems biology 11 (10), 834
  • Quantifying diet-induced metabolic changes of the human gut microbiome
    S Shoaie, P Ghaffari, P Kovatcheva-Datchary, A Mardinoglu, P Sen, ... Cell metabolism 22 (2), 320-331
  • New paradigms for metabolic modeling of human cells
    A Mardinoglu, J Nielsen Current opinion in biotechnology 34, 91-97
  • Tissue-based map of the human proteome
    M Uhlén, L Fagerberg, BM Hallström, C Lindskog, P Oksvold, ... Science 347 (6220)
  • Reconstruction of genome-scale active metabolic networks for 69 human cell types and 16 cancer types using INIT
    R Agren, S Bordel, A Mardinoglu, N Pornputtapong, I Nookaew, J Nielsen PLoS Comput Biol 8 (5), e1002518
  • A Gene Co-Expression Network-Based Drug Repositioning Approach Identifies Candidates for Treatment of Hepatocellular Carcinoma
    Meng Yuan, Koeun Shong, Xiangyu Li, Sajda Ashraf, Mengnan Shi, Woonghee Kim, Jens Nielsen, Hasan Turkez, Saeed Shoaie, Mathias Uhlen, Cheng Zhang, Adil Mardinoglu Cancers 14 (6), 1573
  • Prediction of drug candidates for clear cell renal cell carcinoma using a systems biology-based drug repositioning approach
    Xiangyu Li, Koeun Shong, Woonghee Kim, Meng Yuan, Hong Yang, Yusuke Sato, Haruki Kume, Seishi Ogawa, Hasan Turkez, Saeed Shoaie, Jan Boren, Jens Nielsen, Mathias Uhlen, Cheng Zhang, Adil Mardinoglu EBioMedicine 78, 103963.